Christopher Yau and Kaspar Martens have contributed to an article Bayesian statistics and modelling for the new Nature Reviews Methods Primer journal.
Link to paper
Christopher Yau appeared on the Hugo Rifkind on Times.Radio with Dame Janet Thornton and Tech Journalist Tom Chivers to discuss artificial intelligence and the recent AlphaFold2 development by Google Deepmind.
Hugo Rifkind, Times.Radio
Bulk whole genome sequencing (WGS) enables the analysis of tumor evolution but, because of depth limitations, can only identify old mutational events. The discovery of current mutational processes for predicting the tumor’s evolutionary trajectory requires dense sequencing of individual clones or single cells. Such studies, however, are inherently problematic because of the discovery of excessive false positive mutations when sequencing picogram quantities of DNA. Data pooling to increase the confidence in the discovered mutations, moves the discovery back in the past to a common ancestor.
The PHG Foundation has published a report on Artificial intelligence for genomic medicine. Christopher Yau is very pleased to have been able to share his experience and insight into the subjects covered in this report.