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• Author Correction: Concordance of randomised controlled trials for artificial intelligence interventions with the CONSORT-AI reporting guidelines
• Concordance of randomised controlled trials for artificial intelligence interventions with the CONSORT-AI reporting guidelines
• Reporting guidelines for clinical trial reports for interventions involving artificial intelligence: the CONSORT-AI extension
• The Oxford Classic can identify HGSOC patients who may benefit from EMT-targeting therapies
• An atlas of genetic scores to predict multi-omic traits
• Artificial Intelligence for Multiple Long-term conditions (AIM): A consensus statement from the NIHR AIM consortia
• Detection and evaluation of signals associated with exposure to individual and combination of medications in pregnancy: a signal detection study protocol
• Key outcomes for reporting in studies of pregnant women with multiple long-term conditions: a qualitative study
• Maternal and child outcomes for pregnant women with pre-existing multiple long-term conditions: protocol for an observational study in the UK
• Polypharmacy during pregnancy and associated risk factors: a retrospective analysis of 577 medication exposures among 1.5 million pregnancies in the UK, 2000-2019
• Sociodemographic characteristics and longitudinal progression of multimorbidity: A multistate modelling analysis of a large primary care records dataset in England
• The development of a core outcome set for studies of pregnant women with multimorbidity
• Author Correction: Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation
• Epidemiology of pre-existing multimorbidity in pregnant women in the UK in 2018: a population-based cross-sectional study
• Genetically personalised organ-specific metabolic models in health and disease
• In simulated data and health records, latent class analysis was the optimum multimorbidity clustering algorithm
• Investigating the stability of multimorbidity clusters within and between clustering algorithms, in simulated and health record data
• Patient derived organoids confirm that PI3K/AKT signalling is an escape pathway for radioresistance and a target for therapy in rectal cancer
• Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation (vol 9, 476, 2018)
• Adipocyte-like signature in ovarian cancer minimal residual disease identifies metabolic vulnerabilities of tumor initiating cells
• Bayesian statistics and modelling
• Epidemiology of pre-existing multimorbidity in pregnant women in the UK in 2018: a cross-sectional study
• Patient derived organoids reveal that PI3K/AKT signalling is an escape pathway for radioresistance and a target for therapy in rectal cancer
• Promises and challenges of adoptive T-cell therapies for solid tumours
• Protocol for the development of a core outcome set for studies of pregnant women with pre-existing multimorbidity
• The Oxford classic links epithelial-to-mesenchymal transition to immunosuppression in poor prognosis ovarian cancers
• Genomic profiling in pancreatic cancer reveals spatial genetic heterogeneity but spatial transcriptomic homogeneity
• Guidelines for clinical trial protocols for interventions involving artificial intelligence: the SPIRIT-AI extension
• Reporting guidelines for clinical trial reports for interventions involving artificial intelligence: the CONSORT-AI extension
• The repertoire of serous ovarian cancer non-genetic heterogeneity revealed by single-cell sequencing of normal fallopian tube epithelial cells
• Defective tubulin detyrosination causes structural brain abnormalities with cognitive deficiency in humans and mice
• Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma
• Uncovering the long tail of oesophageal cancer driver genes for patient stratification
• Identification of Subtypes of Barrett's Esophagus and Esophageal Adenocarcinoma Based on DNA Methylation Profiles and Integration of Transcriptome and Genome Data Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium, May 2020, In: Gastroenterology. 158, 6, p. 1682-1697. e1 Research output: Contribution to journal> Article
• NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease
• Separation of dual oxidase 2 and lactoperoxidase expression in intestinal crypts and species differences may limit hydrogen peroxide scavenging during mucosal healing in mice and humans
• Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation
• Colorectal cancer cell line proteomes are representative of primary tumors and predict drug sensitivity
• Germline mutations in PALB2, BRCA1, and RAD51C, which regulate DNA recombination repair, in patients with gastric cancer
• Latin American Gastric Cancer Genetics Collaborative G, Taylor PR, Goldstein AM, Torres J, Echeverry M, Ruiz-Ponte C, Teixeira MR, Carvajal-Carmona LG. Germline mutations in PALB2, BRCA1, and RAD51C, which regulate DNA recombination repair, in patients with gastric cancer
• Premalignant SOX2 overexpression in the fallopian tubes of ovarian cancer patients: Discovery and validation studies
• Salt-inducible kinase 2 couples ovarian cancer cell metabolism with survival at the adipocyte-rich metastatic niche
• Factors influencing success of clinical genome sequencing across a broad spectrum of disorders
• Erythrocytosis associated with a novel missense mutation in the BPGM gene
• Hamming ball auxiliary sampling for factorial hidden Markov models
• The Identification of Further Minimal Regions of Overlap in Chronic Lymphocytic Leukemia Using High-Resolution SNP Arrays
• Towards Response Prediction Using Integrated Genomics in Chronic Lymphocytic Leukaemia: Results on 250 First-Line FCR Treated Patients from UK Clinical Trials
• Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden
• Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion
• Comprehensive genome-wide analysis of CLL samples from UK 1st line and relapsed/refractory clinical trials
• Genome analysis of colorectal cancers in British Bangladeshis identifies early onset and a high prevalence of rbfox1 deletion compared to Caucasians
• Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations
• Quantification of subclonal distributions of recurrent genomic aberrations in paired pre-treatment and relapse samples from patients with B-cell chronic lymphocytic leukemia
• A statistical approach for detecting genomic aberrations in heterogeneous tumor samples from single nucleotide polymorphism genotyping data
• Quantitative Whole Genome Analysis of Sequential Samples From Patients with B-CLL Identifies Novel Recurrent Copy Number Alterations Involving Critical B-Cell Transcription Factors