Lena Rai,
Antonella Ravaggi,
Eliana Bignotti,
Robb Hollis,
Joel Nulsen,
Leticia Campo,
Alistair Easton,
Mara Artibani,
Mike Churchman,
Federico Ferrari,
Others
(2024).
The Oxford Classic can identify HGSOC patients who may benefit from EMT-targeting therapies.
Cancer Research.
Xiaoxuan Liu,
Samantha Cruz Rivera,
David Moher,
Melanie J Calvert,
Alastair K Denniston,
AW Chan,
A Darzi,
C Holmes,
C Yau,
H Ashrafian,
Others
(2024).
Reporting guidelines for clinical trial reports for interventions involving artificial intelligence: the CONSORT-AI extension.
Scientific Journals and Newsletters/Revistas Cientı́ficas y Boletines.
Alexander PL Martindale,
Benjamin Ng,
Victoria Ngai,
Aditya U Kale,
Lavinia Ferrante Di Ruffano,
Robert M Golub,
Gary S Collins,
David Moher,
Melissa D McCradden,
Lauren Oakden-Rayner,
Others
(2024).
Concordance of randomised controlled trials for artificial intelligence interventions with the CONSORT-AI reporting guidelines.
Nature communications.
Alexander PL Martindale,
Carrie D Llewellyn,
Richard O De Visser,
Benjamin Ng,
Victoria Ngai,
Aditya U Kale,
Lavinia Ferrante Di Ruffano,
Robert M Golub,
Gary S Collins,
David Moher,
Others
(2024).
Author Correction: Concordance of randomised controlled trials for artificial intelligence interventions with the CONSORT-AI reporting guidelines.
nature communications.
Siang Ing Lee,
Stephanie Hanley,
Zoe Vowles,
Rachel Plachcinski,
Ngawai Moss,
Megha Singh,
Chris Gale,
Adeniyi Francis Fagbamigbe,
Amaya Azcoaga-Lorenzo,
Anuradhaa Subramanian,
Others
(2023).
The development of a core outcome set for studies of pregnant women with multimorbidity.
BMC medicine.
Sida Chen,
Tom Marshall,
Christopher Jackson,
Jennifer Cooper,
Francesca Crowe,
Krish Nirantharakumar,
Catherine L Saunders,
Paul Kirk,
Sylvia Richardson,
Duncan Edwards,
Others
(2023).
Sociodemographic characteristics and longitudinal progression of multimorbidity: A multistate modelling analysis of a large primary care records dataset in England.
PLoS Medicine.
Anuradhaa Subramanian,
Amaya Azcoaga-Lorenzo,
Astha Anand,
Katherine Phillips,
Siang Ing Lee,
Neil Cockburn,
Adeniyi Francis Fagbamigbe,
Christine Damase-Michel,
Christopher Yau,
Colin McCowan,
Others
(2023).
Polypharmacy during pregnancy and associated risk factors: a retrospective analysis of 577 medication exposures among 1.5 million pregnancies in the UK, 2000-2019.
BMC medicine.
Siang Ing Lee,
Holly Hope,
Dermot O'Reilly,
Lisa Kent,
Gillian Santorelli,
Anuradhaa Subramanian,
Ngawai Moss,
Amaya Azcoaga-Lorenzo,
Adeniyi Francis Fagbamigbe,
Catherine Nelson-Piercy,
Others
(2023).
Maternal and child outcomes for pregnant women with pre-existing multiple long-term conditions: protocol for an observational study in the UK.
BMJ open.
Siang Ing Lee,
Stephanie Hanley,
Zoe Vowles,
Rachel Plachcinski,
Amaya Azcoaga-Lorenzo,
Beck Taylor,
Catherine Nelson-Piercy,
Colin McCowan,
Dermot O'Reilly,
Holly Hope,
Others
(2023).
Key outcomes for reporting in studies of pregnant women with multiple long-term conditions: a qualitative study.
BMC pregnancy and childbirth.
Anuradhaa Subramanian,
Siang Ing Lee,
Sudasing Pathirannehelage Buddhika Hemali Sudasinghe,
Steven Wambua,
Katherine Phillips,
Megha Singh,
Amaya Azcoaga-Lorenzo,
Neil Cockburn,
Jingya Wang,
Adeniyi Fagbamigbe,
Others
(2023).
Detection and evaluation of signals associated with exposure to individual and combination of medications in pregnancy: a signal detection study protocol.
BMJ open.
Hajira Dambha-Miller,
Andrew Farmer,
Krishnarajah Nirantharakumar,
Thomas Jackson,
Christopher Yau,
Lauren Walker,
Iain Buchan,
Sarah Finer,
Michael Robert Barnes,
Nick J Reynolds,
Others
(2023).
Artificial Intelligence for Multiple Long-term conditions (AIM): A consensus statement from the NIHR AIM consortia.
NIHR open research.
Yu Xu,
Scott C Ritchie,
Yujian Liang,
Paul RHJ Timmers,
Maik Pietzner,
Loı̈c Lannelongue,
Samuel a Lambert,
Usman a Tahir,
Sebastian May-Wilson,
Carles Foguet,
Others
(2023).
An atlas of genetic scores to predict multi-omic traits.
Nature.
Yiyan Zheng,
Ritika Sethi,
Lingegowda S Mangala,
Charlotte Taylor,
Juliet Goldsmith,
Ming Wang,
Kenta Masuda,
Eli M Carrami,
David Mannion,
Fabrizio Miranda,
Others
(2022).
Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation (vol 9, 476, 2018).
NATURE COMMUNICATIONS.
Kasun Wanigasooriya,
Joao D Barros-Silva,
Louise Tee,
Mohammed E El-Asrag,
Agata Stodolna,
Oliver J Pickles,
Joanne Stockton,
Claire Bryer,
Rachel Hoare,
Celina M Whalley,
Others
(2022).
Patient derived organoids confirm that PI3K/AKT signalling is an escape pathway for radioresistance and a target for therapy in rectal cancer.
Frontiers in oncology.
L Nichols,
T Taverner,
F Crowe,
S Richardson,
C Yau,
S Kiddle,
P Kirk,
J Barrett,
K Nirantharakumar,
Simon Griffin,
Others
(2022).
Investigating the stability of multimorbidity clusters within and between clustering algorithms, in simulated and health record data.
Elsevier.
Linda Nichols,
Tom Taverner,
Francesca Crowe,
Sylvia Richardson,
Christopher Yau,
Steven Kiddle,
Paul Kirk,
Jessica Barrett,
Krishnarajah Nirantharakumar,
Simon Griffin,
Others
(2022).
In simulated data and health records, latent class analysis was the optimum multimorbidity clustering algorithm.
Journal of clinical epidemiology.
Carles Foguet Coll,
Yu Xu,
Scott Ritchie,
Samuel Lambert,
Elodie Persyn,
Artika Nath,
Emma E Davenport,
David J Roberts,
Dirk S Paul,
Emanuele Di Angelantonio,
Others
(2022).
Genetically personalised organ-specific metabolic models in health and disease.
Nature Research.
Siang Ing Lee,
Amaya Azcoaga-Lorenzo,
Utkarsh Agrawal,
Jonathan I Kennedy,
Adeniyi Francis Fagbamigbe,
Holly Hope,
Anuradhaa Subramanian,
Astha Anand,
Beck Taylor,
Catherine Nelson-Piercy,
Others
(2022).
Epidemiology of pre-existing multimorbidity in pregnant women in the UK in 2018: a population-based cross-sectional study.
BMC pregnancy and childbirth.
Yiyan Zheng,
Ritika Sethi,
Lingegowda S Mangala,
Charlotte Taylor,
Juliet Goldsmith,
Ming Wang,
Kenta Masuda,
Eli M Carrami,
David Mannion,
Fabrizio Miranda,
Others
(2022).
Author Correction: Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.
Nature communications.
Zhiyuan Hu,
Paula Cunnea,
Zhe Zhong,
Haonan Lu,
Oloruntoba I Osagie,
Leticia Campo,
Mara Artibani,
Katherine Nixon,
Jennifer Ploski,
Laura Santana Gonzalez,
Others
(2021).
The Oxford classic links epithelial-to-mesenchymal transition to immunosuppression in poor prognosis ovarian cancers.
Clinical Cancer Research.
Siang Ing Lee,
Kelly-Ann Eastwood,
Ngawai Moss,
Amaya Azcoaga-Lorenzo,
Anuradhaa Subramanian,
Astha Anand,
Beck Taylor,
Catherine Nelson-Piercy,
Christopher Yau,
Colin McCowan,
Others
(2021).
Protocol for the development of a core outcome set for studies of pregnant women with pre-existing multimorbidity.
BMJ open.
Matteo Morotti,
Ashwag Albukhari,
Abdulkhaliq Alsaadi,
Mara Artibani,
James D Brenton,
Stuart M Curbishley,
Tao Dong,
Michael L Dustin,
Zhiyuan Hu,
Nicholas McGranahan,
Others
(2021).
Promises and challenges of adoptive T-cell therapies for solid tumours.
British journal of cancer.
Kasun Wanigasooriya,
Joao D Barros-Silva,
Louise Tee,
Mohammed E El-Asrag,
Agata Stodolna,
Oliver J Pickles,
Joanne Stockton,
Claire Bryer,
Rachel Hoare,
Celina Whalley,
Others
(2021).
Patient derived organoids reveal that PI3K/AKT signalling is an escape pathway for radioresistance and a target for therapy in rectal cancer.
bioRxiv.
Siang Ing Lee,
Amaya Azcoaga-Lorenzo,
Utkarsh Agrawal,
Jonathan I Kennedy,
Adeniyi Francis Fagbamigbe,
Holly Hope,
Anuradhaa Subramanian,
Astha Anand,
Beck Taylor,
Catherine Nelson-Piercy,
Others
(2021).
Epidemiology of pre-existing multimorbidity in pregnant women in the UK in 2018: a cross-sectional study.
The Lancet.
Rens Van De Schoot,
Sarah Depaoli,
Ruth King,
Bianca Kramer,
Kaspar Märtens,
Mahlet G Tadesse,
Marina Vannucci,
Andrew Gelman,
Duco Veen,
Joukje Willemsen,
Others
(2021).
Bayesian statistics and modelling.
Nature Reviews Methods Primers.
Mara Artibani,
Kenta Masuda,
Zhiyuan Hu,
Pascal C Rauher,
Garry Mallett,
Nina Wietek,
Matteo Morotti,
Kay Chong,
Mohammad KaramiNejadRanjbar,
Christos E Zois,
Others
(2021).
Adipocyte-like signature in ovarian cancer minimal residual disease identifies metabolic vulnerabilities of tumor initiating cells.
JCI insight.
Zhiyuan Hu,
Mara Artibani,
Abdulkhaliq Alsaadi,
Nina Wietek,
Matteo Morotti,
Tingyan Shi,
Zhe Zhong,
Laura Santana Gonzalez,
Salma El-Sahhar,
Eli M Carrami,
Others
(2020).
The repertoire of serous ovarian cancer non-genetic heterogeneity revealed by single-cell sequencing of normal fallopian tube epithelial cells.
Cancer cell.
Xiaoxuan Liu,
Samantha Cruz Rivera,
David Moher,
Melanie J Calvert,
Alastair K Denniston,
Hutan Ashrafian,
Andrew L Beam,
An-Wen Chan,
Gary S Collins,
Ara DarziJonathan J Deeks,
Others
(2020).
Reporting guidelines for clinical trial reports for interventions involving artificial intelligence: the CONSORT-AI extension.
The Lancet Digital Health.
Samantha Cruz Rivera,
Xiaoxuan Liu,
An-Wen Chan,
Alastair K Denniston,
Melanie J Calvert,
Hutan Ashrafian,
Andrew L Beam,
Gary S Collins,
Ara Darzi,
Jonathan J Deeks,
Others
(2020).
Guidelines for clinical trial protocols for interventions involving artificial intelligence: the SPIRIT-AI extension.
The Lancet Digital Health.
Shivan Sivakumar,
Anas Rana,
Chandan Seth,
Ines De Santiago,
Zahir Soonawalla,
Robert Morgan,
Aniko Rendek,
Michael Silva,
Srikanth Reddy,
Stephanie Jones,
Others
(2020).
Genomic profiling in pancreatic cancer reveals spatial genetic heterogeneity but spatial transcriptomic homogeneity.
Pancreatology.
Lorena Benedetti,
Thanos Mourikis,
Elisabeth Foxall,
Damjan Temelkovski,
Joel Nulsen,
Juliane Perner,
Matteo Cereda,
Christopher Yau,
Rebecca Fitzgerald,
Michael Howell,
Others
(2019).
Uncovering the long tail of oesophageal cancer driver genes for patient stratification.
BRITISH JOURNAL OF CANCER.
Thanos P Mourikis,
Lorena Benedetti,
Elizabeth Foxall,
Damjan Temelkovski,
Joel Nulsen,
Juliane Perner,
Matteo Cereda,
Jesper Lagergren,
Michael Howell,
Christopher Yau,
Others
(2019).
Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma.
Nature communications.
Alistair T Pagnamenta,
Pierre Heemeryck,
Hilary C Martin,
Christophe Bosc,
Leticia Peris,
Ivy Uszynski,
Sylvie Gory-Fauré,
Simon Couly,
Charu Deshpande,
Ata Siddiqui,
Others
(2019).
Defective tubulin detyrosination causes structural brain abnormalities with cognitive deficiency in humans and mice.
Human Molecular Genetics.
Yiyan Zheng,
Ritika Sethi,
Lingegowda S Mangala,
Charlotte Taylor,
Juliet Goldsmith,
Ming Wang,
Kenta Masuda,
Eli M Carrami,
David Mannion,
Fabrizio Miranda,
Others
(2018).
Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.
Nature communications.
Alice Rigoni,
Richard Poulsom,
Rosemary Jeffery,
Shameer Mehta,
Amy Lewis,
Christopher Yau,
Eleni Giannoulatou,
Roger Feakins,
James O Lindsay,
Mario P Colombo,
Others
(2018).
Separation of dual oxidase 2 and lactoperoxidase expression in intestinal crypts and species differences may limit hydrogen peroxide scavenging during mucosal healing in mice and humans.
Inflammatory bowel diseases.
T Schwerd,
RV Bryant,
Sujeet Pandey,
Melania Capitani,
L Meran,
Jean-Baptiste Cazier,
J Jung,
K Mondal,
M Parkes,
CG Mathew,
Others
(2018).
NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease.
Mucosal immunology.
D Temelkovski,
J Nulsen,
J Perner,
M Cereda,
J Lagergren,
M Howell,
C Yau,
RC Fitzgerald,
P Scaffidi,
JA Somarelli,
Others
(2018).
Identification of Subtypes of Barrett's Esophagus and Esophageal Adenocarcinoma Based on DNA Methylation Profiles and Integration of Transcriptome and Genome Data Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium, May 2020, In: Gastroenterology. 158, 6, p. 1682-1697. e1 Research output: Contribution to journal> Article.
Nature Communications.
R Sahasrabudhe,
P Lott,
M Bohorquez,
T Toal,
AP Estrada,
JJ Suarez,
A Brea-Fernandez,
J Cameselle-Teijeiro,
C Pinto,
I Ramos,
Others
(2017).
Latin American Gastric Cancer Genetics Collaborative G, Taylor PR, Goldstein AM, Torres J, Echeverry M, Ruiz-Ponte C, Teixeira MR, Carvajal-Carmona LG. Germline mutations in PALB2, BRCA1, and RAD51C, which regulate DNA recombination repair, in patients with gastric cancer.
Gastroenterology.
Ruta Sahasrabudhe,
Paul Lott,
Mabel Bohorquez,
Ted Toal,
Ana P Estrada,
John J Suarez,
Alejandro Brea-Fernández,
José Cameselle-Teijeiro,
Carla Pinto,
Irma Ramos,
Others
(2017).
Germline mutations in PALB2, BRCA1, and RAD51C, which regulate DNA recombination repair, in patients with gastric cancer.
Gastroenterology.
Jing Wang,
Dmitri Mouradov,
Xiaojing Wang,
Robert N Jorissen,
Matthew C Chambers,
Lisa J Zimmerman,
Suhas Vasaikar,
Christopher G Love,
Shan Li,
Kym Lowes,
Others
(2017).
Colorectal cancer cell line proteomes are representative of primary tumors and predict drug sensitivity.
Gastroenterology.
Fabrizio Miranda,
David Mannion,
Shujuan Liu,
Yiyan Zheng,
Lingegowda S Mangala,
Clara Redondo,
Sandra Herrero-Gonzalez,
Ruoyan Xu,
Charlotte Taylor,
Donatien Fotso Chedom,
Others
(2016).
Salt-inducible kinase 2 couples ovarian cancer cell metabolism with survival at the adipocyte-rich metastatic niche.
Cancer cell.
Karin Hellner,
Fabrizio Miranda,
Donatien Fotso Chedom,
Sandra Herrero-Gonzalez,
Daniel M Hayden,
Rick Tearle,
Mara Artibani,
Eli M Carrami,
Ruth Williams,
Kezia Gaitskell,
Others
(2016).
Premalignant SOX2 overexpression in the fallopian tubes of ovarian cancer patients: Discovery and validation studies.
EBioMedicine.
Jenny C Taylor,
Hilary C Martin,
Stefano Lise,
John Broxholme,
Jean-Baptiste Cazier,
Andy Rimmer,
Alexander Kanapin,
Gerton Lunter,
Simon Fiddy,
Chris Allan,
Others
(2015).
Factors influencing success of clinical genome sequencing across a broad spectrum of disorders.
Nature genetics.
J-B Cazier,
SR Rao,
CM McLean,
AK Walker,
BJ Wright,
EEM Jaeger,
Christiana Kartsonaki,
L Marsden,
C Yau,
Carme Camps,
Others
(2014).
Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden.
Nature communications.
Ruth M Clifford,
Pauline Robbe,
Susanne Weller,
Adele T Timbs,
Michalis Titsias,
Adam Burns,
Maite Cabes,
Reem Alsolami,
Christopher Yau,
Angela Hamblin,
Others
(2014).
Towards Response Prediction Using Integrated Genomics in Chronic Lymphocytic Leukaemia: Results on 250 First-Line FCR Treated Patients from UK Clinical Trials.
Blood.
Samantha JL Knight,
Ruth Clifford,
Pauline Robbe,
Sara DC Ramos,
Adam Burns,
Adele T Timbs,
Reem Alsolami,
Susanne Weller,
Angela Hamblin,
Joanne Mason,
Others
(2014).
The Identification of Further Minimal Regions of Overlap in Chronic Lymphocytic Leukemia Using High-Resolution SNP Arrays.
Blood.
Nayia Petousi,
Richard R Copley,
Terence RJ Lappin,
Sally E Haggan,
Celeste M Bento,
Holger Cario,
Melanie J Percy,
Peter J Ratcliffe,
Peter a Robbins,
Mary Frances McMullin,
Others
(2014).
Erythrocytosis associated with a novel missense mutation in the BPGM gene.
Haematologica.
Dmitri Mouradov,
Enric Domingo,
Peter Gibbs,
Robert N Jorissen,
Shan Li,
Pik Ying Soo,
Lara Lipton,
Jayesh Desai,
Havard E Danielsen,
Dahmane Oukrif,
Others
(2013).
Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations.
Official journal of the American College of Gastroenterology| ACG.
N Sengupta,
C Yau,
A Sakthianandeswaren,
D Mouradov,
P Gibbs,
N Suraweera,
J Cazier,
G Polanco-Echeverry,
A Ghosh,
M Thaha,
Others
(2013).
Genome analysis of colorectal cancers in British Bangladeshis identifies early onset and a high prevalence of rbfox1 deletion compared to Caucasians.
P Robbe,
R Clifford,
A Timbs,
A Burns,
M Titsias,
M Cabes,
R Alsolami,
N Khalid,
S Henderson,
J Taylor,
Others
(2013).
Comprehensive genome-wide analysis of CLL samples from UK 1st line and relapsed/refractory clinical trials.
HAEMATOLOGICA.
Neel Sengupta,
Christopher Yau,
Anuratha Sakthianandeswaren,
Dmitri Mouradov,
Peter Gibbs,
Nirosha Suraweera,
Jean-Baptiste Cazier,
Guadalupe Polanco-Echeverry,
Anil Ghosh,
Mohamed Thaha,
Others
(2013).
Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion.
Molecular cancer.
SJL Knight,
C Yau,
R Clifford,
AT Timbs,
E Sadighi Akha,
HM Dréau,
A Burns,
C Ciria,
DG Oscier,
AR Pettitt,
Others
(2012).
Quantification of subclonal distributions of recurrent genomic aberrations in paired pre-treatment and relapse samples from patients with B-cell chronic lymphocytic leukemia.
Leukemia.
Adele Timbs,
Sam Knight,
Elham SadighiAkha,
Adam Burns,
Helene Dreau,
Anne-Marie Hewitt,
Chris Hatton,
Chris Yau,
Chris Holmes,
Jenny Taylor,
Others
(2010).
Quantitative Whole Genome Analysis of Sequential Samples From Patients with B-CLL Identifies Novel Recurrent Copy Number Alterations Involving Critical B-Cell Transcription Factors.
Blood.
Christopher Yau,
Dmitri Mouradov,
Robert N Jorissen,
Stefano Colella,
Ghazala Mirza,
Graham Steers,
Adrian Harris,
Jiannis Ragoussis,
Oliver Sieber,
Christopher C Holmes,
Others
(2010).
A statistical approach for detecting genomic aberrations in heterogeneous tumor samples from single nucleotide polymorphism genotyping data.
Genome biology.