Multimodal Survival Analysis with Locally Deployable Language Models


Date
Nov 18, 2025 12:00 AM

Our research explores how artificial intelligence can improve medical prognosis while protecting patient privacy. We developed a lightweight, locally deployable large language model (LLM) that predicts patient survival by combining information from clinical text, medical records, and genetic data.

Unlike traditional AI systems that depend on cloud computing, our model runs entirely on-site, making it suitable for hospitals with limited computing resources and strict data-security requirements. It not only provides accurate, calibrated survival predictions, but also generates concise, human-readable explanations that help clinicians understand the reasoning behind each estimate.

Tested on real cancer patient data, our approach outperforms existing survival models and demonstrates that trustworthy, interpretable AI can be achieved without compromising privacy or accessibility.

Lead Investigator:

Christopher Yau
Christopher Yau
Professor of Artificial Intelligence

I am Professor of Artificial Intelligence. I am interested in statistical machine learning and its applications in the biomedical sciences.