The repertoire of serous ovarian cancer non-genetic heterogeneity revealed by single-cell sequencing of normal fallopian tube epithelial cells

Abstract

We used single cell sequencing to map the repertoire of cell types in the fallopian tube epithelium of ovarian cancer patients. We discovered six cell subtypes, with one mesenchymal-high HGSOC subtype robustly correlated with poor prognosis.

Publication
Cancer Cell